The triangular relationship between economy, banking, and commerce forms the foundation of modern economic growth, with monetary policy as the central regulatory force shaping trade and business dynamics. This paper explores how monetary policy influences trade flows and business expansion through mechanisms of inflation control, interest rate adjustments, credit allocation, and exchange rate management. The findings reveal that the economy acts as the structural framework for stability and productivity, banking functions as the intermediary that transmits monetary impulses into credit and liquidity, and commerce represents the visible manifestation of these processes in trade and market activity. Evidence from both developed and emerging economies highlights the significance of institutional strength and financial integration in ensuring effective policy transmission. International dimensions, such as the global spillover of U.S. Federal Reserve policies and Singapore’s exchange rate–centered approach, underscore the embeddedness of this triangular system within global markets. The COVID-19 pandemic further illustrated the vulnerabilities of this relationship, as expansionary monetary policies stabilized liquidity but created distortions in unemployment and consumption patterns. Ultimately, the study emphasizes that while monetary policies are indispensable for growth, their effectiveness depends on contextual factors such as institutional frameworks, financial depth, and trade openness. The research contributes to theoretical and empirical debates by integrating perspectives from economics, finance, and commerce, offering insights for policymakers seeking to balance stability with growth in increasingly interconnected economies.